Massimo Delledonne Dipartimento di Biotecnologie
Università degli Studi di Verona




 

    Dr. Massimo Delledonne  

           Professor  
              Department of Biotechnology

           Director
               Functional Genomics Center


    Address:

     Dipartimento di Biotecnologie

     Universita' degli Studi di Verona

     Strada le Grazie 15

     37134 Verona, Italy    
                                                                                          



Announcement: Registration for the Fourth StatSeq workshop of the TD0801 COST Action "Statistical Challenges of the 1000€ genome sequences in plants", which will be held in Verona on the 18th and 19th April 2012, is now open!

Massimo Delledonne received his Ph.D. from Università Cattolica del S. C. in 1994.  During 1995-1998 Delledonne visited Chris Lamb at the Salk Institute for Biological Studies in California, discovering the function of nitric oxide in plant disease resistance. 


Delledonne joined the faculty of University of Verona in 2001 and is currently Full Professor of Genetics (SSD Bio/18) in the Department of Biotechnology. He manages a vigorous research program that emphasizes interdisciplinary approaches to understanding plant biology. His own expertise is in the areas of genetics, molecular biology and genomics, and collaborates with researchers in diverse fields, including biochemistry, physiology, bioinformatics, microbiology, medicine and computer science. Together with his colleague Mario Pezzotti, in January 2007 founded the Center of Functional Genomics. This center is dedicated to the development and use of the new tools that the new genomic technologies are offering to microbial, plant, animal and human biologists

 

Massimo Delledonne has been supported by the EMBO Young Investigator Program




Selected publications from the Plant Biology lab:

  • Delledonne M., Xia Y., Dixon R. and Lamb C. (1998). Nitric oxide functions as a signal in plant disease resistance. Nature 394:585-558 [PDF-file]
  • Solomon M., Belenghi B., Delledonne M., Levine A. (1999). The involvement of cysteine proteases and protease inhibitor genes  in the regulation of programmed cell death in plants. Plant Cell 11:431-443 [PDF-file]
  • Delledonne M., Zeier J., Marocco A., Lamb C. (2001) . Signal interactions between nitric oxide and reactive oxygen intermediates in the plant hypersensitive disease resistance response. Proc. Natl. Acad. Sci. USA 98:13454-13459 [PDF-file]
  • Murgia I., Delledonne M., Soave C. (2002). Nitric oxide mediates iron-induced ferritin accumulation in Arabidopsis thaliana. Plant J. 30:521-528 [PDF-file]
  • Zeier J., Delledonne M., Severi E., Sonoda M., Lamb C. (2004). Genetic elucidation of nitric oxide signaling in incompatible plant-pathogen interactions. Plant Physiol. 136:2875-2886 [PDF-file]
  • Perazzolli M., Dominici P., Romero-Puertas M., Zago E., Zeier J., Sonoda M., Lamb C., Delledonne M. (2004) Arabidopsis non-symbiotic hemoglobin AHb1 modulates nitric oxide bioactivity. Plant Cell 16:2785-2794 [PDF-file]
  • Boccara M., Mills C., Zeier J., Anzi C., Lamb C., Poole R., Delledonne M. (2005)  Flavohaemoglobin HmpX from Erwinia chrysanthemi confers nitrosative stress tolerance and affects the plant hypersensitive reaction by intercepting nitric oxide produced by the host . Plant J. 43:226-237 [PDF-file]
  • Delledonne M. (2005) NO news is good news for plants. Curr. Opin. Plant Biol. 8:390-396 [PDF-file]
  • Zaninotto F., La Camera S., Polverari A., Delledonne M. (2006) Cross talk between reactive nitrogen and oxygen species during the hypersensitive response. Plant Physiol. 141: 379-383 [PDF-file]
  • Zago E., Morsa S., Dat J.F., Alard P., Ferrarini A., Inzè D., Delledonne M., Van Breusegem F. (2006) Nitric oxide- and hydrogen peroxide-responsive gene regulation during cell death induction in tobacco. Plant Physiol. 141: 404-411 [PDF-file]
  • Romero-Puertas M.C., Laxa M., Mattè A., Zaninotto F., Finkemeier I., Jones A.M.E.,  Perazzolli M., Vandelle E., Dietz K.J., Delledonne M. (2007) S-nitrosylation of peroxiredoxin II E promotes peroxynitrite-mediated tyrosine nitration. Plant Cell 19: 4120-4130 [PDF-file]
  • Leitner M., Vandelle E., Gaupels F., Bellin D., Delledonne M. (2009) NO signals in the haze. Curr. Opin. Plant Biol. 12:451–458 [PDF-file]
  • Gaupels F., Spiazzi-Vandelle E., Yang D., Delledonne M. (2011). Detection of peroxynitrite accumulation in Arabidopsis thaliana during the hypersensitive defense response. Nitric Oxide 25:222-228 [PDF-file]


Selected publications from the Functional Genomics lab:

  • The French–Italian Public Consortium for Grapevine Genome Characterization (coauthors from Verona are Massimo Delledonne and Mario Pezzotti) (2007). The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla. Nature 449: 463-467 [PDF-file]
  • Denoeud F., Aury JM., Da Silva C., Noel B., Rogier O., Delledonne M., Morgante M., Valle G.,  Wincker P., Scarpelli C., Jaillon O., Artiguenave F. (2008) Annotating genomes with massive-scale RNA-sequencing. Genome Biology [PDF-file]
  • Bellin D., Ferrarini A., Chimento A., Kaiser O., Levenkova N., Bouffard P., Delledonne M. (2009). Combining next-generation pyrosequencing with microarray for large scale expression analysis in non-model species. BMC Genomics 10: 555  [PDF-file]
  • Ventura M., Turroni F., Zomer A., Foroni E., Giubellini V., Bottacini F., Canchaya C., Claesson M.J., He F., Mantzourani M., Mulas L., Ferrarini A., Gao B., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Gupta R.S., Zhang Z., Beighton D., Fitzgerald G.F., O’Toole P.W., van Sinderen D. (2009). The Bifidobacterium dentium Bd1 genome sequence reflects its genetic adaptation to the human oral cavity. PLoS Genetics 5(12): e1000785 [PDF-file]
  • Zenoni S., Ferrarini A., Giacomelli E., Xumerle L., Fasoli M., Malerba G., Bellin D., Pezzotti M., Delledonne M. (2010) Characterization of transcriptional complexity during berry development in Vitis vinifera using RNA-Seq.  Plant Physiol. 152: 1787-1795 [PDF-file]
  • Zamboni A., Di Carli M., Guzzo F., Stocchero M., Zenoni S., Ferrarini A., Tononi P., Toffali K., Desiderio A., Lilley K., Pè E., Benvenuto E., Delledonne M., Pezzotti M. Identification of putative stage-specific grapevine berry biomarkers and omics data integration into networks. Plant Physiol. 154: 1439-1459 [PDF-file]
  • The International Cancer Genome Consortium. (2010). International network of cancer genome projects. Nature 464:993-998 [PDF-file]
  • Turroni F., Bottacini F., Foroni E., Mulder I., Kim J.H., Zomer A., Garcia B.S., Bidossi A., Ferrarini A., Giubellini V., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Fitzgerald G.F., Mills D., Margolles A., Kelly D., van Sinderen D., Ventura M. (2010). Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging. Proc Natl Acad Sci. USA 107: 19514-19519 [PDF-file]
  • Mele C., Iatropoulos P., Donadelli R., Calabria A., Maranta R., Cassis P., Buelli S., Tomasoni S., Piras R., Krendel M., Bettoni S., Morigi M., Delledonne M., Pecoraro C., Abbate I., Capobianchi M.R., Hildebrandt F., Otto E., Schaefer F., Macciardi F., Ozaltin F., Emre S., Ibsirlioglu T., Benigni A., Remuzzi G. and Noris M. (2011). MYO1E mutations and childhood familial focal segmental glomerulosclerosis. New Engl. J. Med. 365 : 295-306  [PDF-file]

In press:

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For more information, please visit the Delledonne lab homepage

Last update January 21st, 2012