Roberto
Chignola
Publications in extenso (full list by year)
Publications in extenso (full list by year)
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Scientific interests
Short CV
List of Publications
by year
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Scientific interests
Short CV
List of Publications
by year
by research field
For students
Other interests
(57) ANTONIO GLIOZZI, CATERINA GUIOT,
ROBERTO CHIGNOLA, PIERPAOLO DELSANTO
Oscillations in the growth of multicellular tumor spheroids: a revisited quantitative approach.
Cell Proliferation (2009), in press
(56) CARLO TOMELLERI, CHIARA DALLA PELLEGRINA, ROBERTO CHIGNOLA
Microplate spectrophotometry for the high-throughput screening of cytotoxic molecules.
Cell Proliferation (2009), in press
(55) EDOARDO MILOTTI, ALESSIO DEL FABBRO, ROBERTO CHIGNOLA
Numerical integration methods for large-scale biophysical simulations.
Computer Physics Communications (2009), 180: 2166-2174.
(54) ROBERTO CHIGNOLA, Studio della crescita di popolazioni biologiche interagenti, in: A. Burato, R. Chignola, L. Corso, Simulazione del comportamento dinamico di sistemi preda-predatore, I Quaderni del Marconi - Quaderni Didattici, Verona, Gente del Marconi, 2009, pp. 9-24.
(53) CHIARA DALLA PELLEGRINA, OMAR PERBELLINI, MARIA TERESA SCUPOLI, CARLO TOMELLERI, CHIARA ZANETTI, GIANNI ZOCCATELLI, MARINA FUSI, ANGELO PERUFFO, CORRADO RIZZI, ROBERTO CHIGNOLA
Effects of wheat germ agglutinin on human gastrointestinal epithelium: insights from an experimental model of immune/epithelial cell interaction.
Toxicology and Applied Pharmacology (2009) 237: 146-153.
(52) EDOARDO MILOTTI , ALESSIO DEL FABBRO, CHIARA DALLA PELLEGRINA, ROBERTO CHIGNOLA.
Statistical approach to the analysis of cell desynchronization data.
Physica A - Statistical Mechanics and its Application (2008) 387: 4204-4214.
(51) EDOARDO MILOTTI, ROBERTO CHIGNOLA, CHIARA DALLA PELLEGRINA, ALESSIO DEL FABBRO, MARCELLO FARINA, DIEGO LIBERATI.
VBL: Virtual Biophysics Lab.
Il Nuovo Cimento (2008) 31C: 109-118.
(50) CARLO TOMELLERI, EDOARDO MILOTTI, CHIARA DALLA PELLEGRINA, OMAR PERBELLINI, ALESSIO DEL FABBRO, MARIA TERESA SCUPOLI, ROBERTO CHIGNOLA.
A quantitative study on the growth variability of tumour cell clones in vitro.
Cell Proliferation (2008), 41: 177-191.
(49) ROBERTO CHIGNOLA, Matematica e radioterapia dei tumori, in: A.Burato, R.Chignola, F.Castelli, L.Corso, G.Pezzo, S.Zuccher, Matematica e radioterapia dei tumori: sviluppo e applicazioni di un modello predittivo semplificato, I quaderni del Marconi - Quaderni didattici, Verona, Gente del Marconi, 2007, pp. 9-21.
(48) GIANNI ZOCCATELLI, CHIARA DALLA PELLEGRINA, MARICA CONSOLINI, MARINA FUSI, STEFANO SFORZA, GIANCARLO AQUINO, ARNALDO DOSSENA, ROBERTO CHIGNOLA, ANGELO PERUFFO, MARIO OLIVIERI, CORRADO RIZZI.
Isolation and identification of two lipid transfer proteins in pomegranate (Punica granatum).
J. Agr. Food Chem. (2007), 55: 11057-11062.
(47) ROBERTO CHIGNOLA, ALESSIO DEL FABBRO, CHIARA DALLA PELLEGRINA, EDOARDO MILOTTI.
Ab initio phenomenological simulation of the growth of large tumor cell population.
Physical Biology (2007) 4: 114-133.
(46) EDOARDO MILOTTI, ALESSIO DEL FABBRO, CHIARA DALLA PELLEGRINA, ROBERTO CHIGNOLA.
Dynamics of allosteric action in multisite protein modification.
Physica A - Statistical Mechanics and its Application (2007), 379: 133-150
(45) GIANNI ZOCCATELLI, CHIARA DALLA PELLEGRINA, SILVIA MOSCONI MARICA CONSOLINI, GIANLUCA VENERI, ROBERTO CHIGNOLA, ANGELO PERUFFO, CORRADO RIZZI.
Full-fledged proteomic analysis of bioactive wheat amylase inhibitors by a three-dimensional analytical technique: Identification of new heterodimeric aggregation states.
Electrophoresis (2007), 28: 460-466.
(44) ROBERTO CHIGNOLA, Il problema biologico in , R.Chignola, F.Castelli, L.Corso, G.Pezzo, S.Zuccher La biomatematica in un problema di oncologia, I quaderni del Marconi - Quaderni didattici, Verona, Gente del Marconi, 2006, pp. 8-25.
(43) ROBERTO CHIGNOLA, CHIARA DALLA PELLEGRINA, ALESSIO DEL FABBRO, EDOARDO MILOTTI.
Thresholds, long delays and stability from generalized allosteric effect in protein networks.
Physica A - Statistical Mechanics and its Application (2006), 371: 463-472.
(42) ROBERTO CHIGNOLA, PAOLO DAI PRA, LAURA MARIA MORATO, PAOLA SIRI.
Proliferation and death in a binary environment: a stochastic model of cellular ecosystems.
Bulletin of Mathematical Biology (2006), 68: 1661-1680.
(41) GIANLUCA VENERI, GIANNI ZOCCATELLI, SILVIA MOSCONI, CHIARA DALLA PELLEGRINA, ROBERTO CHIGNOLA, CORRADO RIZZI.
A rapid method for the recovery, quantification and electrophoretic analysis of proteins from beer.
Journal of the Institute of Brewing (2006), 112: 26-27.
(40) ROBERTO CHIGNOLA, ALESSIO DEL FABBRO, ROBERTO FORONI, EDOARDO MILOTTI.
Modellizzazione biofisica per la crescita dei tumori solidi.
Automazione e Strumentazione (2005) 10: 87-93.
(39) CHIARA DALLA PELLEGRINA, CORRADO RIZZI, SILVIA MOSCONI, GIANNI ZOCCATELLI, ANGELO PERUFFO and ROBERTO CHIGNOLA.
Plant lectins as carriers for oral drugs: is wheat germ agglutinin a suitable candidate?
Toxicology and Applied Pharmacology (2005), 207: 170-178.
(38) CHIARA DALLA PELLEGRINA, GIORGIA PADOVANI, FEDERICA MAINENTE, GIANNI ZOCCATELLI, GAETANO BISSOLI, SILVIA MOSCONI, GIANLUCA VENERI, ANGELO PERUFFO, GIANCARLO ANDRIGHETTO, CORRADO RIZZI and ROBERTO CHIGNOLA.
Anti-tumour potential of a gallic acid-containing phenolic fraction from Oenothera biennis.
Cancer Letters (2005), 226: 17-25.
(37) ROBERTO CHIGNOLA, ALESSIO DEL FABBRO, ROBERTO FORONI, EDOARDO MILOTTI.
Crescita dei tumori solidi: un approccio multidisciplinare che attraversa la fenomenologia e la modellizzazione biofisica per approdare alla clinica.
Proceedings of "BIOSYS 2005, Sistemi di Ingegneria Biomedica", Milano, 9-10 Giugno 2005, pp. 1-16
(36) ROBERTO CHIGNOLA and EDOARDO MILOTTI.
A phenomenological approach to the simulation of metabolism and proliferation dynamics of large tumor cell populations.
Physical Biology (2005), 2: 8-22.
(35) SIMONE VINCENZI, SILVIA MOSCONI, GIANNI ZOCCATELLI, CHIARA DALLA PELLEGRINA, GIANLUCA VENERI, ROBERTO CHIGNOLA, ANGELO PERUFFO, ANDREA CURIONI and CORRADO RIZZI.
Protein recovery from wine and their quantification: development of a new procedure.
American Journal of Enology and Viticulture (2005), 56: 182-187.
(34) ROBERTO CHIGNOLA and ROBERTO FORONI.
Estimating the growth kinetics of experimental tumours from as few as two determinations of tumour size: implications for clinical oncology.
IEEE Transactions on Biomedical Engineering (2005), 52: 808-815.
(33) E.STEFANI, M.G.TESTI, A.MATUCCI, R.CHIGNOLA, T.CESTARI, S.DALLA SANTA, A.ZOSO, A.ROSATO, G.TRIDENTE, G.ANDRIGHETTO and S.SARTORIS.
Induction and expansion of an anti-tumor immune response by B7-1+ tumor cells in dependence on the anatomical site of delivery and the dose applied.
Proceedings of Immunology 2004, Montreal, Canada (2004), pp.521-524
(32) ROBERTO CHIGNOLA and EDOARDO MILOTTI.
Numerical simulation of tumor spheroid dynamics.
Physica A (2004), 338: 261-266.
(31) CHIARA DALLA PELLEGRINA, ANDREA MATUCCI, GIANNI ZOCCATELLI, CORRADO RIZZI, SIMONE VINCENZI, GIANLUCA VENERI, GIANCARLO ANDRIGHETTO, ANGELO PERUFFO and ROBERTO CHIGNOLA.
Studies on the joint cytotoxicity of wheat germ agglutinin and monensin.
Toxicology in Vitro (2004), 18: 821-827.
(30) ANDREA MATUCCI, GIANLUCA VENERI, CHIARA DALLA PELLEGRINA, GIANNI ZOCCATELLI, SIMONE VINCENZI, ROBERTO CHIGNOLA, ANGELO D.B.PERUFFO and CORRADO RIZZI.
Temperature-dependent decay of Wheat Germ Agglutinin activity and its implications for food processing and analysis.
Food Control (2004), 15: 391-395.
(29) SILVIA SARTORIS, MARIA GRAZIA TESTI, ELISABETTA STEFANI, ROBERTO CHIGNOLA, CHIARA GUERRIERO, ANDREA MATUCCI, TIZIANA CESTARI, ALDO SCARPA, ANNA PIA RIVIERA, GIOVANNA ZANONI, GIUSEPPE TRIDENTE and GIANCARLO ANDRIGHETTO.
The induction of an anti-tumor adaptive immune response elicited by tumor cells expressing de novo B7-1 mainly depends on the anatomic site of their delivery. The dose applied regulates the expansion of the response.
Immunology (2003), 11: 474-481.
(28) CORRADO RIZZI, LUISA GALEOTO, GIANNI ZOCCATELLI, SIMONE VINCENZI, ROBERTO CHIGNOLA and ANGELO D.B. PERUFFO.
Active soybean lectin in foods: quantitative determination by ELISA using immobilised asialofetuin.
Food Res. Int. (2003), 36: 815-821.
(27) CHIARA GUERRIERO, GIANNI ZOCCATELLI, ELISABETTA STEFANI, SILVIA SARTORIS, TIZIANA CESTARI, ANNA PIA RIVIERA, GIUSEPPE TRIDENTE, GIANCARLO ANDRIGHETTO and ROBERTO CHIGNOLA.
Myelin basic protein epitopes secreted by human T cells encounter natural autoantibodies in the serum.
J. Neuroimm. (2003), 141: 83-89.
(26) CORRADO RIZZI, ROBERTO CHIGNOLA, GIANNI ZOCCATELLI, MASSIMO DONA’, ANGELO D.B. PERUFFO, UGO CARRARO and KATIA ROSSINI.
Effects of a Wheat Germ-enriched diet on skeletal muscle regeneration in Whistar rats
Ital. J. Food Sci. (2003), 15: 417-425.
(25) GIANNI ZOCCATELLI, CHIARA DALLA PELLEGRINA, SIMONE VINCENZI, CORRADO RIZZI, ROBERTO CHIGNOLA and ANGELO D.B. PERUFFO.
Egg-matrix for large-scale single-step affinity purification of plant lectins with different carbohydrate specificities.
Protein Expr. Purif. (2003), 27: 182-185.
(24) SIMONE VINCENZI, GIANNI ZOCCATELLI, FABIO PERBELLINI, CORRADO RIZZI, ROBERTO CHIGNOLA, ANDREA CURIONI and ANGELO PERUFFO.
Quantitative determination of dietary lectin activities by enzyme-linked immunosorbent assay using specific glycoproteins immobilized on microtiter plates.
J. Agric. Food Chem. (2002), 50: 6266-6270.
(23) ROBERTO CHIGNOLA, CORRADO RIZZI, SIMONE VINCENZI, TIZIANA CESTARI, NADIA BRUTTI, ANNA PIA RIVIERA, SILVIA SARTORIS, ANGELO D.B. PERUFFO and GIANCARLO ANDRIGHETTO.
Effects of dietary wheat germ deprivation on the immune system in whistar rats: a pilot study.
Int. Immunopharm. (2002), 2:1495-1501.
(22) ROBERTO CHIGNOLA, GIANCARLO ANDRIGHETTO and DIEGO LIBERATI.
Aggregati sperimentali di cellule tumorali: studio della crescita.
Automazione e Strumentazione (2001), 9: 113-115.
(21) ROBERTO CHIGNOLA, GIANCARLO ANDRIGHETTO and DIEGO LIBERATI.
Analysis of biomedical signals: growth of experimental tumour cell aggregates.
In: Health and Medical Systems: Information and Control Technologies, D.Liberati ed., (2001) pp. 141-148.
(20) ROBERTO CHIGNOLA, TIZIANA CESTARI, CHIARA GUERRIERO, ANNAPIA RIVIERA, SERGIO FERRARI, ANDREA BRENDOLAN, MARIALUISA GOBBO, SARA AMATO, SILVIA SARTORIS, GIULIO FRACASSO, MARIA GRAZIA LIUZZI, PAOLO RICCIO, GIUSEPPE TRIDENTE and GIANCARLO ANDRIGHETTO.
Expression of myelin basic protein (MBP)-like epitopes in human non-neural cells revealed by two anti-MBP IgM monoclonal antibodies.
Clin. Exp. Immunol. (2000), 122: 429-436.
(19) SILVIA SARTORIS, ANDREA BRENDOLAN, ALEXA DEGOLA, MARIA GRAZIA TESTI, ROBERTO CHIGNOLA, ALDO SCARPA, MARIA SCARDONI, GIOVANNA CONTRERAS, LEONARDO PINELLI, CLAUDIO LUNARDI, RUGGERO BERI, CINZIA PERA, G.BATTISTA FERRARA, ANNA PIA RIVIERA, GIUSEPPE TRIDENTE and GIANCARLO ANDRIGHETTO.
Analysis of CIITA encoding AIR-1 gene promoters in insulin dependent diabetes mellitus and rheumatoid arthritis patients from the northeast of italy: absence of sequence variability.
Human Immunol. (2000), 61: 599-604.
(18) ROBERTO CHIGNOLA, ALESSANDRO SCHENETTI, GIANCARLO ANDRIGHETTO, ELENA CHIESA, ROBERTO FORONI, SILVIA SARTORIS, GIUSEPPE TRIDENTE and DIEGO LIBERATI.
Forecasting the growth of multicell tumour spheroids: implications for the dynamic growth of solid tumours.
Cell Prolif. (2000), 33: 219-229.
(17) ROBERTO CHIGNOLA, DIEGO LIBERATI, ELENA CHIESA, CRISTINA ANSELMI, ROBERTO FORONI, SILVIA SARTORIS, ANDREA BRENDOLAN, GIUSEPPE TRIDENTE and GIANCARLO ANDRIGHETTO.
A non-parametric method for the analysis of experimental tumour growth data.
Med. Biol. Eng. Comput. (1999), 37:537-542.
(16) ROBERTO CHIGNOLA, ALESSANDRO SCHENETTI, ELENA CHIESA, ROBERTO FORONI, SILVIA SARTORIS, ANDREA BRENDOLAN, GIUSEPPE TRIDENTE, GIANCARLO ANDRIGHETTO and DIEGO LIBERATI.
Oscillating growth patterns of multicellular tumour spheroids.
Cell Prolif. (1999), 32:39-48.
(15) ROBERTO CHIGNOLA, DIEGO LIBERATI, ELENA CHIESA, ROBERTO FORONI, GIANCARLO ANDRIGHETTO, GIUSEPPE TRIDENTE AND MARCO COLOMBATTI.
On the growth dynamics of multicellular tumor spheroids: a preliminar report.
In: Chaos Fractals Models, F.M. Guindani and G. Salvadori eds., Italian University Press, Pavia (1998), pp. 371-377.
(14) ROBERTO CHIGNOLA, CRISTINA ANSELMI, MAURO DALLA SERRA, ANTONIA FRANCESCHI, GIULIO FRACASSO, MARCELLA PASTI, ELENA CHIESA, MICHAEL J. LORD, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Self-potentiation of ligand-toxin conjugates containing ricin A chain fused with viral structures.
J. Biol. Chem. (1995), 270:23345-23351.
(13) ROBERTO CHIGNOLA, ROBERTO FORONI, ANTONIA FRANCESCHI, MARCELLA PASTI, CAROLA CANDIANI, CRISTINA ANSELMI, GIULIO FRACASSO, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Heterogeneous response of individual multicellular tumor spheroids to immunotoxins and ricin toxin.
Br. J. Cancer (1995), 72:607-614.
(12) ROBERTO CHIGNOLA, MARCELLA PASTI, CAROLA CANDIANI, ANTONIA FRANCESCHI, CRISTINA ANSELMI, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Escape mechanisms of human leukemic cells to long-term immunotoxin treatment in an in vitro experimental model.
Int. J. Cancer (1995), 61:535-541.
(11) ROBERTO CHIGNOLA, ROBERTO FORONI, CAROLA CANDIANI, ANTONIA FRANCESCHI, MARCELLA PASTI, GABRIELLA STEVANONI, CRISTINA ANSELMI, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Cytoreductive effects of anti transferrin receptor immunotoxins in a multicellular tumor spheroid model.
Int. J. Cancer (1994), 57:268-274.
(10) ROBERTO CHIGNOLA, CRISTINA ANSELMI, ANTONIA FRANCESCHI, MARCELLA PASTI, CAROLA CANDIANI, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Sensitivity of human leukemia cells in exponential or stationary growth phase to anti-CD5 immunotoxins. Role of intracellular processing events.
J. Immunol. (1994), 152:2333-2343.
(9) ANTONIA FRANCESCHI, FRANCO DOSIO, CRISTINA ANSELMI, ROBERTO CHIGNOLA, CAROLA CANDIANI, MARCELLA PASTI, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Mechanisms involved in serum dependent inactivation of the immunotoxin enhancers monensin and carrier protein-monensin.
Eur. J. Biochem. (1994), 219:469-479.
(8) GIUSEPPINA BENONI, CAROLA CANDIANI, ANTONIA FRANCESCHI, ROBERTO CHIGNOLA, MARCELLA PASTI, LAURA CUZZOLIN, CRISTINA ANSELMI, GABRIELLA STEVANONI, GISEPPE TRIDENTE and MARCO COLOMBATTI.
Disposition of intrathecally administered immunotoxins in rats. A preliminary report.
Pharmacol. Res. (1992), 25:290-291, suppl.2.
(7) CAROLA CANDIANI, ANTONIA FRANCESCHI, ROBERTO CHIGNOLA, MARCELLA PASTI, CRISTINA ANSELMI, GIUSEPPINA BENONI, GIUSEPPE TRIDENTE, and MARCO COLOMBATTI.
Blocking effect of human serum but not of cerebrospinal fluid on ricin A chain immunotoxin potentiation by monensin or carrier protein-monensin conjugates.
Cancer Res. (1992), 52:623-630.
(6) CAROLA CANDIANI, CRISTINA ANSELMI, ROBERTO CHIGNOLA, ANTONIA FRANCESCHI, MONICA BRENTEGANI, GIUSEPPE TRIDENTE, and MARCO COLOMBATTI.
Potentiation of cytotoxic heteroconjugates by monensin-carrier proteins.
J. Chemoter. (1991), 3:351-353 suppl..
(5) MARCO COLOMBATTI, ROBERTO CHIGNOLA, CAROLA CANDIANI, ANTONIA FRANCESCHI, CRISTINA ANSELMI, and GIUSEPPE TRIDENTE.
Immunotoxins synthesized with ricin or diphtheria toxin: mechanisms of action and improvement of their anti-tumor cell efficacy.
J. Chemother. (1991), 3:341-344 suppl..
(4) NICOLA FRANZOLIN, GIAMPAOLO BIANCHI, PAOLO BELTRAMI, ROBERTO CHIGNOLA, ROMEO PIANON, ANTONIO D'AMICO, LUIGI SALVATORE AZZOLINA, GIUSEPPE TRIDENTE E GAETANO MOBILIO.
Il ruolo dell'analisi del DNA mediante citometria a flusso nell'identificare i falsi positivi citologici da flogosi.
Acta Urol. Ital. (1991), 6:505-507, suppl.1.
(3) ROBERTO CHIGNOLA, MARCO COLOMBATTI, LORENA DELL'ARCIPRETE, CAROLA CANDIANI, and GIUSEPPE TRIDENTE.
Distribution of endocytosed molecules to intracellular acidic environments correlates with immunotoxin activity.
Int. J. Cancer (1990), 46:1117-1123.
(2) MARCO COLOMBATTI, ROBERTO CHIGNOLA, CAROLA CANDIANI, CRISTINA ANSELMI, and GIUSEPPE TRIDENTE.
Problems and potentials in immunotoxin therapy.
In: Immunological aspects of malignant lymphomas and cryoglobulinemia, F.Dammacco ed., Edi-Ermes, Milano (1990) pp.147-159.
(1) MARCO COLOMBATTI, LORENA DELL'ARCIPRETE, ROBERTO CHIGNOLA, and GIUSEPPE TRIDENTE.
Carrier protein-monensin conjugates: enhancement of immunotoxin cytotoxicity and potential in tumor treatment.
Cancer Research (1990), 50:1385-1391
Oscillations in the growth of multicellular tumor spheroids: a revisited quantitative approach.
Cell Proliferation (2009), in press
(56) CARLO TOMELLERI, CHIARA DALLA PELLEGRINA, ROBERTO CHIGNOLA
Microplate spectrophotometry for the high-throughput screening of cytotoxic molecules.
Cell Proliferation (2009), in press
(55) EDOARDO MILOTTI, ALESSIO DEL FABBRO, ROBERTO CHIGNOLA
Numerical integration methods for large-scale biophysical simulations.
Computer Physics Communications (2009), 180: 2166-2174.
(54) ROBERTO CHIGNOLA, Studio della crescita di popolazioni biologiche interagenti, in: A. Burato, R. Chignola, L. Corso, Simulazione del comportamento dinamico di sistemi preda-predatore, I Quaderni del Marconi - Quaderni Didattici, Verona, Gente del Marconi, 2009, pp. 9-24.
(53) CHIARA DALLA PELLEGRINA, OMAR PERBELLINI, MARIA TERESA SCUPOLI, CARLO TOMELLERI, CHIARA ZANETTI, GIANNI ZOCCATELLI, MARINA FUSI, ANGELO PERUFFO, CORRADO RIZZI, ROBERTO CHIGNOLA
Effects of wheat germ agglutinin on human gastrointestinal epithelium: insights from an experimental model of immune/epithelial cell interaction.
Toxicology and Applied Pharmacology (2009) 237: 146-153.
(52) EDOARDO MILOTTI , ALESSIO DEL FABBRO, CHIARA DALLA PELLEGRINA, ROBERTO CHIGNOLA.
Statistical approach to the analysis of cell desynchronization data.
Physica A - Statistical Mechanics and its Application (2008) 387: 4204-4214.
(51) EDOARDO MILOTTI, ROBERTO CHIGNOLA, CHIARA DALLA PELLEGRINA, ALESSIO DEL FABBRO, MARCELLO FARINA, DIEGO LIBERATI.
VBL: Virtual Biophysics Lab.
Il Nuovo Cimento (2008) 31C: 109-118.
(50) CARLO TOMELLERI, EDOARDO MILOTTI, CHIARA DALLA PELLEGRINA, OMAR PERBELLINI, ALESSIO DEL FABBRO, MARIA TERESA SCUPOLI, ROBERTO CHIGNOLA.
A quantitative study on the growth variability of tumour cell clones in vitro.
Cell Proliferation (2008), 41: 177-191.
(49) ROBERTO CHIGNOLA, Matematica e radioterapia dei tumori, in: A.Burato, R.Chignola, F.Castelli, L.Corso, G.Pezzo, S.Zuccher, Matematica e radioterapia dei tumori: sviluppo e applicazioni di un modello predittivo semplificato, I quaderni del Marconi - Quaderni didattici, Verona, Gente del Marconi, 2007, pp. 9-21.
(48) GIANNI ZOCCATELLI, CHIARA DALLA PELLEGRINA, MARICA CONSOLINI, MARINA FUSI, STEFANO SFORZA, GIANCARLO AQUINO, ARNALDO DOSSENA, ROBERTO CHIGNOLA, ANGELO PERUFFO, MARIO OLIVIERI, CORRADO RIZZI.
Isolation and identification of two lipid transfer proteins in pomegranate (Punica granatum).
J. Agr. Food Chem. (2007), 55: 11057-11062.
(47) ROBERTO CHIGNOLA, ALESSIO DEL FABBRO, CHIARA DALLA PELLEGRINA, EDOARDO MILOTTI.
Ab initio phenomenological simulation of the growth of large tumor cell population.
Physical Biology (2007) 4: 114-133.
(46) EDOARDO MILOTTI, ALESSIO DEL FABBRO, CHIARA DALLA PELLEGRINA, ROBERTO CHIGNOLA.
Dynamics of allosteric action in multisite protein modification.
Physica A - Statistical Mechanics and its Application (2007), 379: 133-150
(45) GIANNI ZOCCATELLI, CHIARA DALLA PELLEGRINA, SILVIA MOSCONI MARICA CONSOLINI, GIANLUCA VENERI, ROBERTO CHIGNOLA, ANGELO PERUFFO, CORRADO RIZZI.
Full-fledged proteomic analysis of bioactive wheat amylase inhibitors by a three-dimensional analytical technique: Identification of new heterodimeric aggregation states.
Electrophoresis (2007), 28: 460-466.
(44) ROBERTO CHIGNOLA, Il problema biologico in , R.Chignola, F.Castelli, L.Corso, G.Pezzo, S.Zuccher La biomatematica in un problema di oncologia, I quaderni del Marconi - Quaderni didattici, Verona, Gente del Marconi, 2006, pp. 8-25.
(43) ROBERTO CHIGNOLA, CHIARA DALLA PELLEGRINA, ALESSIO DEL FABBRO, EDOARDO MILOTTI.
Thresholds, long delays and stability from generalized allosteric effect in protein networks.
Physica A - Statistical Mechanics and its Application (2006), 371: 463-472.
(42) ROBERTO CHIGNOLA, PAOLO DAI PRA, LAURA MARIA MORATO, PAOLA SIRI.
Proliferation and death in a binary environment: a stochastic model of cellular ecosystems.
Bulletin of Mathematical Biology (2006), 68: 1661-1680.
(41) GIANLUCA VENERI, GIANNI ZOCCATELLI, SILVIA MOSCONI, CHIARA DALLA PELLEGRINA, ROBERTO CHIGNOLA, CORRADO RIZZI.
A rapid method for the recovery, quantification and electrophoretic analysis of proteins from beer.
Journal of the Institute of Brewing (2006), 112: 26-27.
(40) ROBERTO CHIGNOLA, ALESSIO DEL FABBRO, ROBERTO FORONI, EDOARDO MILOTTI.
Modellizzazione biofisica per la crescita dei tumori solidi.
Automazione e Strumentazione (2005) 10: 87-93.
(39) CHIARA DALLA PELLEGRINA, CORRADO RIZZI, SILVIA MOSCONI, GIANNI ZOCCATELLI, ANGELO PERUFFO and ROBERTO CHIGNOLA.
Plant lectins as carriers for oral drugs: is wheat germ agglutinin a suitable candidate?
Toxicology and Applied Pharmacology (2005), 207: 170-178.
(38) CHIARA DALLA PELLEGRINA, GIORGIA PADOVANI, FEDERICA MAINENTE, GIANNI ZOCCATELLI, GAETANO BISSOLI, SILVIA MOSCONI, GIANLUCA VENERI, ANGELO PERUFFO, GIANCARLO ANDRIGHETTO, CORRADO RIZZI and ROBERTO CHIGNOLA.
Anti-tumour potential of a gallic acid-containing phenolic fraction from Oenothera biennis.
Cancer Letters (2005), 226: 17-25.
(37) ROBERTO CHIGNOLA, ALESSIO DEL FABBRO, ROBERTO FORONI, EDOARDO MILOTTI.
Crescita dei tumori solidi: un approccio multidisciplinare che attraversa la fenomenologia e la modellizzazione biofisica per approdare alla clinica.
Proceedings of "BIOSYS 2005, Sistemi di Ingegneria Biomedica", Milano, 9-10 Giugno 2005, pp. 1-16
(36) ROBERTO CHIGNOLA and EDOARDO MILOTTI.
A phenomenological approach to the simulation of metabolism and proliferation dynamics of large tumor cell populations.
Physical Biology (2005), 2: 8-22.
(35) SIMONE VINCENZI, SILVIA MOSCONI, GIANNI ZOCCATELLI, CHIARA DALLA PELLEGRINA, GIANLUCA VENERI, ROBERTO CHIGNOLA, ANGELO PERUFFO, ANDREA CURIONI and CORRADO RIZZI.
Protein recovery from wine and their quantification: development of a new procedure.
American Journal of Enology and Viticulture (2005), 56: 182-187.
(34) ROBERTO CHIGNOLA and ROBERTO FORONI.
Estimating the growth kinetics of experimental tumours from as few as two determinations of tumour size: implications for clinical oncology.
IEEE Transactions on Biomedical Engineering (2005), 52: 808-815.
(33) E.STEFANI, M.G.TESTI, A.MATUCCI, R.CHIGNOLA, T.CESTARI, S.DALLA SANTA, A.ZOSO, A.ROSATO, G.TRIDENTE, G.ANDRIGHETTO and S.SARTORIS.
Induction and expansion of an anti-tumor immune response by B7-1+ tumor cells in dependence on the anatomical site of delivery and the dose applied.
Proceedings of Immunology 2004, Montreal, Canada (2004), pp.521-524
(32) ROBERTO CHIGNOLA and EDOARDO MILOTTI.
Numerical simulation of tumor spheroid dynamics.
Physica A (2004), 338: 261-266.
(31) CHIARA DALLA PELLEGRINA, ANDREA MATUCCI, GIANNI ZOCCATELLI, CORRADO RIZZI, SIMONE VINCENZI, GIANLUCA VENERI, GIANCARLO ANDRIGHETTO, ANGELO PERUFFO and ROBERTO CHIGNOLA.
Studies on the joint cytotoxicity of wheat germ agglutinin and monensin.
Toxicology in Vitro (2004), 18: 821-827.
(30) ANDREA MATUCCI, GIANLUCA VENERI, CHIARA DALLA PELLEGRINA, GIANNI ZOCCATELLI, SIMONE VINCENZI, ROBERTO CHIGNOLA, ANGELO D.B.PERUFFO and CORRADO RIZZI.
Temperature-dependent decay of Wheat Germ Agglutinin activity and its implications for food processing and analysis.
Food Control (2004), 15: 391-395.
(29) SILVIA SARTORIS, MARIA GRAZIA TESTI, ELISABETTA STEFANI, ROBERTO CHIGNOLA, CHIARA GUERRIERO, ANDREA MATUCCI, TIZIANA CESTARI, ALDO SCARPA, ANNA PIA RIVIERA, GIOVANNA ZANONI, GIUSEPPE TRIDENTE and GIANCARLO ANDRIGHETTO.
The induction of an anti-tumor adaptive immune response elicited by tumor cells expressing de novo B7-1 mainly depends on the anatomic site of their delivery. The dose applied regulates the expansion of the response.
Immunology (2003), 11: 474-481.
(28) CORRADO RIZZI, LUISA GALEOTO, GIANNI ZOCCATELLI, SIMONE VINCENZI, ROBERTO CHIGNOLA and ANGELO D.B. PERUFFO.
Active soybean lectin in foods: quantitative determination by ELISA using immobilised asialofetuin.
Food Res. Int. (2003), 36: 815-821.
(27) CHIARA GUERRIERO, GIANNI ZOCCATELLI, ELISABETTA STEFANI, SILVIA SARTORIS, TIZIANA CESTARI, ANNA PIA RIVIERA, GIUSEPPE TRIDENTE, GIANCARLO ANDRIGHETTO and ROBERTO CHIGNOLA.
Myelin basic protein epitopes secreted by human T cells encounter natural autoantibodies in the serum.
J. Neuroimm. (2003), 141: 83-89.
(26) CORRADO RIZZI, ROBERTO CHIGNOLA, GIANNI ZOCCATELLI, MASSIMO DONA’, ANGELO D.B. PERUFFO, UGO CARRARO and KATIA ROSSINI.
Effects of a Wheat Germ-enriched diet on skeletal muscle regeneration in Whistar rats
Ital. J. Food Sci. (2003), 15: 417-425.
(25) GIANNI ZOCCATELLI, CHIARA DALLA PELLEGRINA, SIMONE VINCENZI, CORRADO RIZZI, ROBERTO CHIGNOLA and ANGELO D.B. PERUFFO.
Egg-matrix for large-scale single-step affinity purification of plant lectins with different carbohydrate specificities.
Protein Expr. Purif. (2003), 27: 182-185.
(24) SIMONE VINCENZI, GIANNI ZOCCATELLI, FABIO PERBELLINI, CORRADO RIZZI, ROBERTO CHIGNOLA, ANDREA CURIONI and ANGELO PERUFFO.
Quantitative determination of dietary lectin activities by enzyme-linked immunosorbent assay using specific glycoproteins immobilized on microtiter plates.
J. Agric. Food Chem. (2002), 50: 6266-6270.
(23) ROBERTO CHIGNOLA, CORRADO RIZZI, SIMONE VINCENZI, TIZIANA CESTARI, NADIA BRUTTI, ANNA PIA RIVIERA, SILVIA SARTORIS, ANGELO D.B. PERUFFO and GIANCARLO ANDRIGHETTO.
Effects of dietary wheat germ deprivation on the immune system in whistar rats: a pilot study.
Int. Immunopharm. (2002), 2:1495-1501.
(22) ROBERTO CHIGNOLA, GIANCARLO ANDRIGHETTO and DIEGO LIBERATI.
Aggregati sperimentali di cellule tumorali: studio della crescita.
Automazione e Strumentazione (2001), 9: 113-115.
(21) ROBERTO CHIGNOLA, GIANCARLO ANDRIGHETTO and DIEGO LIBERATI.
Analysis of biomedical signals: growth of experimental tumour cell aggregates.
In: Health and Medical Systems: Information and Control Technologies, D.Liberati ed., (2001) pp. 141-148.
(20) ROBERTO CHIGNOLA, TIZIANA CESTARI, CHIARA GUERRIERO, ANNAPIA RIVIERA, SERGIO FERRARI, ANDREA BRENDOLAN, MARIALUISA GOBBO, SARA AMATO, SILVIA SARTORIS, GIULIO FRACASSO, MARIA GRAZIA LIUZZI, PAOLO RICCIO, GIUSEPPE TRIDENTE and GIANCARLO ANDRIGHETTO.
Expression of myelin basic protein (MBP)-like epitopes in human non-neural cells revealed by two anti-MBP IgM monoclonal antibodies.
Clin. Exp. Immunol. (2000), 122: 429-436.
(19) SILVIA SARTORIS, ANDREA BRENDOLAN, ALEXA DEGOLA, MARIA GRAZIA TESTI, ROBERTO CHIGNOLA, ALDO SCARPA, MARIA SCARDONI, GIOVANNA CONTRERAS, LEONARDO PINELLI, CLAUDIO LUNARDI, RUGGERO BERI, CINZIA PERA, G.BATTISTA FERRARA, ANNA PIA RIVIERA, GIUSEPPE TRIDENTE and GIANCARLO ANDRIGHETTO.
Analysis of CIITA encoding AIR-1 gene promoters in insulin dependent diabetes mellitus and rheumatoid arthritis patients from the northeast of italy: absence of sequence variability.
Human Immunol. (2000), 61: 599-604.
(18) ROBERTO CHIGNOLA, ALESSANDRO SCHENETTI, GIANCARLO ANDRIGHETTO, ELENA CHIESA, ROBERTO FORONI, SILVIA SARTORIS, GIUSEPPE TRIDENTE and DIEGO LIBERATI.
Forecasting the growth of multicell tumour spheroids: implications for the dynamic growth of solid tumours.
Cell Prolif. (2000), 33: 219-229.
(17) ROBERTO CHIGNOLA, DIEGO LIBERATI, ELENA CHIESA, CRISTINA ANSELMI, ROBERTO FORONI, SILVIA SARTORIS, ANDREA BRENDOLAN, GIUSEPPE TRIDENTE and GIANCARLO ANDRIGHETTO.
A non-parametric method for the analysis of experimental tumour growth data.
Med. Biol. Eng. Comput. (1999), 37:537-542.
(16) ROBERTO CHIGNOLA, ALESSANDRO SCHENETTI, ELENA CHIESA, ROBERTO FORONI, SILVIA SARTORIS, ANDREA BRENDOLAN, GIUSEPPE TRIDENTE, GIANCARLO ANDRIGHETTO and DIEGO LIBERATI.
Oscillating growth patterns of multicellular tumour spheroids.
Cell Prolif. (1999), 32:39-48.
(15) ROBERTO CHIGNOLA, DIEGO LIBERATI, ELENA CHIESA, ROBERTO FORONI, GIANCARLO ANDRIGHETTO, GIUSEPPE TRIDENTE AND MARCO COLOMBATTI.
On the growth dynamics of multicellular tumor spheroids: a preliminar report.
In: Chaos Fractals Models, F.M. Guindani and G. Salvadori eds., Italian University Press, Pavia (1998), pp. 371-377.
(14) ROBERTO CHIGNOLA, CRISTINA ANSELMI, MAURO DALLA SERRA, ANTONIA FRANCESCHI, GIULIO FRACASSO, MARCELLA PASTI, ELENA CHIESA, MICHAEL J. LORD, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Self-potentiation of ligand-toxin conjugates containing ricin A chain fused with viral structures.
J. Biol. Chem. (1995), 270:23345-23351.
(13) ROBERTO CHIGNOLA, ROBERTO FORONI, ANTONIA FRANCESCHI, MARCELLA PASTI, CAROLA CANDIANI, CRISTINA ANSELMI, GIULIO FRACASSO, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Heterogeneous response of individual multicellular tumor spheroids to immunotoxins and ricin toxin.
Br. J. Cancer (1995), 72:607-614.
(12) ROBERTO CHIGNOLA, MARCELLA PASTI, CAROLA CANDIANI, ANTONIA FRANCESCHI, CRISTINA ANSELMI, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Escape mechanisms of human leukemic cells to long-term immunotoxin treatment in an in vitro experimental model.
Int. J. Cancer (1995), 61:535-541.
(11) ROBERTO CHIGNOLA, ROBERTO FORONI, CAROLA CANDIANI, ANTONIA FRANCESCHI, MARCELLA PASTI, GABRIELLA STEVANONI, CRISTINA ANSELMI, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Cytoreductive effects of anti transferrin receptor immunotoxins in a multicellular tumor spheroid model.
Int. J. Cancer (1994), 57:268-274.
(10) ROBERTO CHIGNOLA, CRISTINA ANSELMI, ANTONIA FRANCESCHI, MARCELLA PASTI, CAROLA CANDIANI, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Sensitivity of human leukemia cells in exponential or stationary growth phase to anti-CD5 immunotoxins. Role of intracellular processing events.
J. Immunol. (1994), 152:2333-2343.
(9) ANTONIA FRANCESCHI, FRANCO DOSIO, CRISTINA ANSELMI, ROBERTO CHIGNOLA, CAROLA CANDIANI, MARCELLA PASTI, GIUSEPPE TRIDENTE and MARCO COLOMBATTI.
Mechanisms involved in serum dependent inactivation of the immunotoxin enhancers monensin and carrier protein-monensin.
Eur. J. Biochem. (1994), 219:469-479.
(8) GIUSEPPINA BENONI, CAROLA CANDIANI, ANTONIA FRANCESCHI, ROBERTO CHIGNOLA, MARCELLA PASTI, LAURA CUZZOLIN, CRISTINA ANSELMI, GABRIELLA STEVANONI, GISEPPE TRIDENTE and MARCO COLOMBATTI.
Disposition of intrathecally administered immunotoxins in rats. A preliminary report.
Pharmacol. Res. (1992), 25:290-291, suppl.2.
(7) CAROLA CANDIANI, ANTONIA FRANCESCHI, ROBERTO CHIGNOLA, MARCELLA PASTI, CRISTINA ANSELMI, GIUSEPPINA BENONI, GIUSEPPE TRIDENTE, and MARCO COLOMBATTI.
Blocking effect of human serum but not of cerebrospinal fluid on ricin A chain immunotoxin potentiation by monensin or carrier protein-monensin conjugates.
Cancer Res. (1992), 52:623-630.
(6) CAROLA CANDIANI, CRISTINA ANSELMI, ROBERTO CHIGNOLA, ANTONIA FRANCESCHI, MONICA BRENTEGANI, GIUSEPPE TRIDENTE, and MARCO COLOMBATTI.
Potentiation of cytotoxic heteroconjugates by monensin-carrier proteins.
J. Chemoter. (1991), 3:351-353 suppl..
(5) MARCO COLOMBATTI, ROBERTO CHIGNOLA, CAROLA CANDIANI, ANTONIA FRANCESCHI, CRISTINA ANSELMI, and GIUSEPPE TRIDENTE.
Immunotoxins synthesized with ricin or diphtheria toxin: mechanisms of action and improvement of their anti-tumor cell efficacy.
J. Chemother. (1991), 3:341-344 suppl..
(4) NICOLA FRANZOLIN, GIAMPAOLO BIANCHI, PAOLO BELTRAMI, ROBERTO CHIGNOLA, ROMEO PIANON, ANTONIO D'AMICO, LUIGI SALVATORE AZZOLINA, GIUSEPPE TRIDENTE E GAETANO MOBILIO.
Il ruolo dell'analisi del DNA mediante citometria a flusso nell'identificare i falsi positivi citologici da flogosi.
Acta Urol. Ital. (1991), 6:505-507, suppl.1.
(3) ROBERTO CHIGNOLA, MARCO COLOMBATTI, LORENA DELL'ARCIPRETE, CAROLA CANDIANI, and GIUSEPPE TRIDENTE.
Distribution of endocytosed molecules to intracellular acidic environments correlates with immunotoxin activity.
Int. J. Cancer (1990), 46:1117-1123.
(2) MARCO COLOMBATTI, ROBERTO CHIGNOLA, CAROLA CANDIANI, CRISTINA ANSELMI, and GIUSEPPE TRIDENTE.
Problems and potentials in immunotoxin therapy.
In: Immunological aspects of malignant lymphomas and cryoglobulinemia, F.Dammacco ed., Edi-Ermes, Milano (1990) pp.147-159.
(1) MARCO COLOMBATTI, LORENA DELL'ARCIPRETE, ROBERTO CHIGNOLA, and GIUSEPPE TRIDENTE.
Carrier protein-monensin conjugates: enhancement of immunotoxin cytotoxicity and potential in tumor treatment.
Cancer Research (1990), 50:1385-1391