Human skeletal muscle: participation of different metabolic activities in oxidation of L-lactate.
Popinigis J; Antosiewicz J; Crimi M; Lenaz G; Wakabayashi T
Department of Bioenergetics, JÀedrzej Sniadecki Academy of Physical Education,
GdaÆnsk-Oliwa, Poland.
Acta Biochim Pol, 1991, 38:1, 169-75
Abstract
The pure mitochondrial fraction obtained from human skeletal muscle did not show coupled L-lactate (+ NAD) oxidation, but this function could be restored by addition of LDH. Thus the "direct", coupled oxidation of L-lactate described earlier (Popinigis et al., 1990. International Perspectives in Exercise Physiology, Human Kinetics Books, pp. 132-133) should be attributed to contaminations.